阿拉丁核酸合成試劑-自主發布-資訊-生物在線

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阿拉丁核酸合成試劑

作者：上海阿拉丁生化科技股份有限公司 2020-06-23T11:00 (訪問量:7000)

d>98%1122-28-75g,25g,100gD1093204,5-二*基咪唑4,5-Dicyanoimidazole99%1122-28-75g,25g,100gT1616122,4,5,6-四甲基苯二磺酰二氯2,4,5,6-Tetramethylbenzenedisulfonyl Dichloride>98.0%(T)97997-76-71g,5gT1389651-(2,4,6-三異丙基苯磺酰)-1,2,4-三唑1-(2,4,6-Triisopropylphenylsulfonyl)-1,2,4-triazole>98.0%(HPLC)54230-60-31g,5g,25gT1061831-對甲基苯磺酰咪唑1-(p-Toluenesulfonyl)imidazole99%2232-08-85g,25g,100g,500gT1093412,4,6-三異丙基苯磺酰氯2,4,6-Triisopropylbenzenesulfonyl chloride97%6553-96-45g,25g,100g,500gD105651N,N'-二環己基-4-嗎啉脒N,N′-Dicyclohexyl-4-morpholinecarboxamidine98%4975-73-95g,25g,100g,500gT1006451,2,4-三氮唑1,2,4-Triazole99%288-88-025g,100g,250g,500gE1113105-乙硫基四氮唑5-(Ethylthio)-1H-tetrazole98%89797-68-21g,5g,25g,100g

羥基保護劑，氨基保護劑

產品號中文名稱英文名稱級別Cas規格
I107549異丁酰氯Isobutyryl Chloride98%79-30-125ml,100ml,500ml,2.5L
H106017六甲基二硅胺烷Hexamethyl disilylamineAR,98%999-97-3100ml,500ml,2.5L,10L
D154192二叔丁基二氯硅烷Di-tert-butyldichlorosilane>95.0%(GC)18395-90-91g,5g
N1066032-**溴化芐2-Nitrobenzyl bromide97%3958-60-95g,25g,100g
P160117苯氧基乙酰氯Phenoxyacetyl Chloride>98.0%(GC)701-99-525g,100g,500g
B1528961,3-苯并二硫代吡咯四氟化硼鹽[羥基保護劑]1,3-Benzodithiolylium Tetrafluoroborate [Hydroxyl-Protecting Agent]>96.0%(T)57842-27-01g,5g
T109041N,O-雙(三甲基硅烷基)乙酰胺N,O-Bis(trimethylsilyl)acetamide95%10416-59-825ml,100ml,500ml,5L
T131644 N,O-雙(三甲基硅烷基)乙酰胺TMS-BA用于GC衍生化10416-59-85ml,25ml
A108664乙酰氯Acetyl chloride99%,無色75-36-5500ml,2.5L
A108662乙酰氯Acetyl chlorideAR,98%75-36-5100ml,500ml,12*500ml,2.5L,10L
C1349682-氯代三苯甲基氯2-Chlorotrityl Chloride≥97.0%42074-68-025g,100g,500g,2.5kg
T109597特戊酰氯Trimethylacetyl chloride98%3282-30-225ml,100ml,500ml,2.5L,10L
D106289N,N-二甲基甲酰胺二甲縮醛DMF-DMA98%,用于酯化4637-24-525g,100g,500g
D106288N,N-二甲基甲酰胺二甲縮醛N,N-Dimethylformamide Dimethyl Acetal97%4637-24-525ml,100ml,500ml
T106184三苯基氯甲烷Trityl Chloride97%76-83-525g,100g,250g,500g,2.5kg
C153889 4-氯苯氧基乙酰氯4-Chlorophenoxyacetyl Chloride>98.0%(T)4122-68-35g,10g,25g,100g,500g
T1093412,4,6-三異丙基苯磺酰氯2,4,6-Triisopropylbenzenesulfonyl chloride97%6553-96-45g,25g,100g,500g
D1092924,4'-二甲氧基三苯基氯甲烷4,4′-Dimethoxytrityl chloride>97.0%40615-36-95g,25g,100g,500g
D119481二叔丁基硅基雙(三氟甲烷磺酸)Di-tert-butylsilyl bis(trifluoromethanesulfonate)97%85272-31-71g,5g,25g
B111191叔丁基二苯基氯硅烷tert-Butyldiphenylchlorosilane98%58479-61-110g,25g,100g,250g
B103644 叔丁基二甲基氯硅烷tert-Butyldimethylsilyl chloride97%18162-48-625g,100g,250g,500g
T1626344,4',4''-三(苯酰氧基)三苯甲基溴[羥基保護劑]4,4',4''-Tris(benzoyloxy)trityl Bromide [Hydroxyl Protecting Agent]>97.0%(T)86610-66-41g,5g,25g
D1135291,3-二氯四甲基二硅氧烷1,3-Dichloro-1,1,3,3-tetramethyldisiloxane95%2401-73-25g,25g,100g
D1391831,3二氯-1,1,3,3-四異丙基二硅氧烷1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane≥97%69304-37-61g,5g,25g,100g
M1006114-甲氧基苯甲酰氯4-Methoxybenzoyl chloride97%100-07-225g,100g,500g
B104566苯甲酰氯Benzoyl chlorideACS, ≥99.0% (T)98-88-4500g
C104814 三甲基氯硅烷(TMCS)Chlorotrimethylsilane≥99.0%(GC)75-77-4100ml,250ml,500ml,2.5L,10L
C104813 三甲基氯硅烷(TMCS)Chlorotrimethylsilane>98.0%(GC)75-77-4100ml,250ml,500ml,2.5L,10L
T106616三氟甲磺酸三甲基硅酯Trimethylsilyl trifluoromethanesulfonate98.00%27607-77-85g,10g,25g,50g,100g,250g,500g
M1135034-甲氧基氯化三苯甲烷4-Monomethoxytrityl chloride97%14470-28-15g,10g,25g,100g,250g
B104818 苯甲酸酐Benzoic anhydride98%93-97-025g,100g,500g

脫保護劑

產品號中文名稱英文名稱級別Cas規格
T103291三氟乙酸（TFA）Trifluoroacetic acidAR,99.0%76-05-1100g,500g,2.5kg
H107501六氟異丙醇1,1,1,3,3,3-Hexafluoro-2-propanol99.50%920-66-1 25g,100g,250g,500g,2.5kg

,
阿拉丁核酸合成試劑

寡核苷酸是短的、單鏈或雙鏈的DNA或RNA分子。其合成方法發展歷程：從Michelson和Todd早期的H-磷酸鹽和磷酸三酯法（H-Phosphonate & Phosphotriester）；到1950年代Khorana的磷酸二酯法（Phosphodiester）；以及1960-1970年代的磷酸三酯法（Phosphotriester）和亞磷酸三酯法（Phosphite triester）的發展。而直至1980年代，Marvin Caruthers的亞磷酰胺法（Phosphoramidite），加上自動化固相技術，成為了目前主流的寡核苷酸合成技術方法。在聚合酶鏈反應(PCR)、核酸測序、基因檢測、核酸藥物研發等領域有廣泛應用。

亞磷酰胺寡聚體的合成在3'-5'方向進行(與生物合成中DNA復制的5'-3'方向相反)。每個合成周期添加一個核苷酸。亞磷酰胺DNA合成循環如圖所示。

亞磷酰胺DNA合成循環

保護核苷

產品號中文名稱英文名稱級別Cas規格
I119475N2-異丁?；?2′-脫氧鳥苷N2-Isobutyryl-2′-deoxyguanosine98%68892-42-2 100mg,250mg,1g,5g
I1195195'-O-(4,4'-二甲氧基三苯基)-N2-異丁?；?2'-脫氧鳥苷N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine99.00%68892-41-11g,5g,10g,25g,100g
N159691N6-二苯甲?；佘?2',3'-二苯甲酸酯N6-Dibenzoyladenosine 2',3'-Dibenzoate>98.0%(HPLC)(T)58463-04-0100mg,1g
B119471N4-苯甲?；?5′-O-(4,4′-二甲氧基三苯基)-2′-脫氧胞苷N4-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine99%67219-55-01g,5g
B103100N4-苯甲酰胞苷N4-Benzoylcytidine98%13089-48-01g,5g,25g
B119532N4-苯甲酰基-2'-脫氧胞苷N4-Benzoyl-2′-deoxycytidine98.00%4836-13-9250mg,1g,5g
B122954N6-苯甲?；?2'-脫氧腺苷水合物N6-Benzoyl-2′-deoxyadenosine hydrate98%206752-42-3,4546-72-9250mg,1g,5g
B119470N6-苯甲?；?5′-O-(4,4′-二甲氧基三苯基)-2′-脫氧腺苷N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine99%64325-78-6100mg,1g,5g
O1176845′-O-(4,4′-二甲氧基三苯甲基)胸苷5′-O-(4,4′-Dimethoxytrityl)thymidine98.00%40615-39-21g,5g,25g
B119477N6-苯甲酰基腺苷N-Benzoyladenosine97%4546-55-81g,5g,25g

核糖，2'-脫氧核糖

產品號中文名稱英文名稱級別Cas規格
R105972L-核糖L-(+)-Ribose98%24259-59-41g,5g,10g,25g,100g
T107915四乙酰核糖1,2,3,5-Tetra-O-acetyl-β-D-ribofuranose98%13035-61-55g,25g,100g,500g
R104821D-(-)-核糖D-(-)-Ribose≥99%（HPLC)50-69-15g,25g,100g,250g,500g
R104820 D-(-)-核糖D-(-)-Ribose98%50-69-1100g,500g,2.5Kg
R103230 1-乙?；?2,3,5-三苯甲酰氧基-1-beta-D-呋喃核糖β-D-Ribofuranose 1-acetate 2,3,5-tribenzoate98%6974-32-91g,5g,25g,100g
M158368甲基-β-D-呋喃核糖苷Methyl β-D-Ribofuranoside>97.0%(HPLC)7473-45-21g,5g,25g,100g
D1210773,5-二-O-(對甲苯酰)-2-脫氧-Α-D-呋喃核糖氯3,5-Di-O-(p-toluyl)-2-deoxy-D-ribofuranosyl chloride90%4330-21-6250mg
D104784 2-脫氧-D-核糖2-Deoxy-D-Ribose98%533-67-51g,5g,25g,100g
D1239892-脫氧-2,2-二氟-D-赤-戊糖酸γ-內酯3,5-二苯甲酸酯2-Deoxy-2,2-difluoro-D-erythro-pentonic Acid γ-Lactone 3,5-Dibenzoate98%122111-01-71g,5g,25g,100g
T1394962-脫氧-2-氟-1,3,5-三-O-苯甲?；?α-D-阿拉伯呋喃糖2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α-D- arabinofuranose-97614-43-21g,5g,25g

硫轉移試劑

產品號中文名稱英文名稱級別Cas規格
X162986氫化黃原素Xanthane Hydride>95.0%(HPLC)6846-35-15g,25g,100g,500g
H157193 3H-1,2-苯并二硫醇-3-酮1,1-二氧化物3H-1,2-Benzodithiol-3-one 1,1-Dioxide>98.0%(HPLC)66304-01-6250mg,1g,5g
B152485雙(苯乙酰)二硫化物Bis(phenylacetyl) Disulfide>98.0%(HPLC)15088-78-55g,25g

磷酸化試劑，磷硫化試劑

    產品號中文名稱英文名稱級別Cas規格
    M157887二氯磷酸甲酯Methyl Phosphorodichloridate>95.0%(T)677-24-75g,25g,100g
    C1194802-*乙基N,N,N′,N′-四異丙基亞磷酰二胺2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphordiamidite97%102691-36-11g,5g,25g,100g
    T162687焦磷酸四芐酯Tetrabenzyl Pyrophosphate>98.0%(HPLC)990-91-0250mg,1g,5g,25g
    P104277二氯化磷酸苯酯Phenyl dichlorophosphate
                                     
    
                                         
    
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