氧化低密度脂蛋白/Human ox-LDL說明書-分析方法-資訊-生物在線

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氧化低密度脂蛋白/Human ox-LDL說明書

作者：上海鈺博生物科技有限公司 2023-03-29T00:00 (訪問量:2449)

?Human ox-LDL

氧化低密度脂蛋白

英文名稱 Human ox-LDL
中文名稱 氧化低密度脂蛋白
別????名 ox-LDL: LDL (Copper oxidized); Cu2SO4 oxidized low density lipoprotein; oxidized low density lipoprotein; Low density lipoprotein; MDA oxidized LDL; MDA oxidized low density lipoprotein; Human ox-LDL ??氧化型低密度脂蛋白;
Specific References??(7)?????|?????bs-1698P has been referenced in 7 publications.
111?[IF=3.466]?Zhang et al. H19 knockdown suppresses proliferation and induces apoptosis by regulating miR-148b/WNT/β-catenin in ox-LDL -stimulated vascular smooth muscle cells. (2018) J.Biomed.Sci. 25:11??other?;??Human.??222
111?[IF=3.514]?Su Q et al. Pinocembrin protects endothelial cells from oxidized LDL-induced injury.Cytokine. 2018 Nov;111:475-480.??Other?;??
111?[IF=3.309]?Ye J et al. LncRBA GSA5, up-regulated by ox-LDL, aggravates inflammatory response and MMP expression in THP-1 macrophages by acting like a sponge for miR-221.Exp Cell Res. 2018 Aug 15;369(2):348-355.??Other?;??
111?[IF=3.647]?Yi Zhou et al. Long non-coding RNA MIAT/miR-148b/PAPPA axis modifies cell proliferation and migration in ox-LDL-induced Human aorta vascular smooth muscle cells. Life Sci. 2020 Sep 1;256:117852.??Other?;??Human.??222
111?[IF=2.1]?Heng-Jing Hu. et al. Hydrogen sulfide improves ox?LDL?induced expression levels of Lp?PLA2?in THP?1 monocytes via the p38MAPK pathway. Mol Med Rep. 2021 May;23(5):1-10??Other?;??
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111?[IF=1.785]?Huiqiong Jiang. et al. MicroRNA?301a?3p increases oxidative stress, inflammation and apoptosis in ox?LDL?induced HUVECs by targeting KLF7. Exp Ther Med. 2021 Jun;21(6):1-8??WB,FC?;??Human.??222
111?[IF=6.986]?Yang, Yilin. et al. Knockdown of lncRNA H19 alleviates ox-LDL-induced HCAECs inflammation and injury by mediating miR-20a-5p/HDAC4 axis. INFLAMM RES. 2022 Jul;:1-13??
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性????狀 Liquid
濃????度 >1.0 mg/ml
物????種 Human
序????列 Purified native protein
內(nèi)毒素 Not analyzed
活性 Not tested
緩?沖?液 10 mM PBS(pH=7.4) with 0.01 μM EDTA.
保存條件 Store at 4°C for 8 weeks. Avoid freeze.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. Low-density lipoprotein oxidised with Cu2SO4.

來源：正常人血漿中分離獲得，經(jīng)銅離子氧化人源血漿低密度脂蛋白;。
純度：98%，(瓊脂糖凝膠電泳)
注意事項：
1. 長時間的儲存后可能會產(chǎn)生沉淀，這種現(xiàn)象屬于正常情況。將溶液放入離心管中離心2分鐘將聚合物除去即可。
2. 高密度脂蛋白相當(dāng)不穩(wěn)定，提前計劃你的實(shí)驗(yàn)，使用新鮮的材料，建議實(shí)驗(yàn)時最好現(xiàn)用現(xiàn)配，采用新鮮配置工作液

本產(chǎn)品僅供科研使用.請勿用于醫(yī)藥,不能用于臨床治療診斷使用！

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